Donor NKG2C Copy Number: An Independent Predictor for CMV Reactivation after Double Cord Blood Transplantation
نویسندگان
چکیده
منابع مشابه
Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen.
We have previously shown that NKG2C(+) NK cells from CMV naive umbilical cord blood grafts expand preferentially in recipients after CMV reactivation, representing a primary NK cell response after hematopoietic cell transplantation. In this study, recipients of adult donor hematopoietic cell transplantation were assessed to evaluate the role of donor/recipient CMV serostatus on the expression a...
متن کاملGuillain-Barré Syndrome due to CMV Reactivation after Cardiac Transplantation
A 40-year-old male patient suffered from end-stage heart failure due to ischemic cardiomyopathy and received orthotopic cardiac transplantation in June 2005. The instantaneous postoperative course was uneventful, but, seven months later, he suffered from paralysis in the lower extremities finally resulting in quadriplegia and was admitted to hospital. After laboratory testings the diagnosis of ...
متن کاملSibling donor cord blood transplantation for thalassemia major: Experience of the Sibling Donor Cord Blood Program.
The Sibling Donor Cord Blood (SDCB) Program was initiated in 1998 as a resource to collect, characterize, and release cord blood units (CBUs) from families affected by malignant and nonmalignant disorders for transplantation. Families in the United States were recruited by telephone after referrals by community and academic physicians. Collection kits were mailed to prospective participants and...
متن کاملDonor CMV serologic status and outcome of CMV-seropositive recipients after unrelated donor stem cell transplantation: an EBMT megafile analysis.
Cytomegalovirus (CMV) has been a major cause of morbidity and mortality after allogeneic stem cell transplantation (SCT). The importance of the recipient's serologic status is paramount. However, the importance of the donor's serologic status in CMV-seropositive recipients is controversial. We analyzed the influence of the donor's CMV status in a large cohort of patients. A total of 7018 patien...
متن کاملDonor CMV serological status and outcome of CMV seropositive recipients after unrelated donor stem cell transplantation; An EBMT Megafile analysis
1. Dept of Hematology, Huddinge University Hospital, Stockholm, Sweden 2. Department of Medical Statistics, Leiden University Medical Centre, Leiden, the Netherlands 3. Department of Medicine, University Hospital, Tübingen, Germany 4. Department of Hematology, Ospedale San Martino, Genova , Italy 5. Department. of Haematology/Oncology, University of Leipzig. Leipzig, Germany 6. Department of. H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-99-114407